A-PRF™ | Advanced Platelet Rich Fibrin
Chairside adgang til patientens helingspotentiale fra venøs blod
The concept of PRF (Platelet Rich Fibrin) is based on the centrifugation of whole blood without anticoagulants. (J. Choukroun et al. 2001). At the end of the spin, a fibrin clot containing the majority of the platelets and white blood cells is obtained.
This fibrin clot called Platelet Riche Fibrin or PRF will release gradually growth factors or cytokines in the site (VEGF, PDGF, TGF Beta, Thrombospondin)
Advanced Platelet Rich Fibrin (A-PRF™) is the latest protocol from Choukroun utilizing the Low Speed Concept to capture more cells and proteins and provide a significantly higher release during a 10 day period, than regular PRF!
The expected objective of these growth factors is to accelerate the soft tissue and bone healing.
Numerous international publications are available and demonstrate the effectiveness of PRF in many indications: oral surgery (implants, bone grafting, periodontal surgery, extractions, etc…) and also in Orthopedic, Gastro and dermatological surgery.
A-PRF™ | The process & application
A-PRF™ | Phlebotomy
Venous blood is drawn into A-PRF™ 10 ml tubes. This is done fast and each tube is placed into the centrifuge. Time is critical.
A-PRF™ | Spin
The A-PRF™ tubes are placed into the DUO centrifuge. It can hold 12 tubes. The protocol is pre-programmet and spin the tubes for 8 minutes. After the spin the lit opens and the next step can be performed.
A-PRF™ | Compression
The RBC are removed from the clot and the plasma clot is placed in the PRF box. A double lit is placed on top and in few minutes the exudate is removed from the clot and a each clot is turned into a fibrin membrane.
A-PRF™ | sticky bone
A-PRF™ fibrin membranes cut into pieces and mixed with biomaterials to get growth factors releases inside the graft.
A-PRF™ | PRF membrane
A-PRF™ used to cover the augmented site either alone or outside a barrier membrane.
A-PRF™ | Sinus
A-PRF™ membrane closed any Schneider membrane rupture and protect the same from sharp edges on biomaterials
A-PRF™ | Eksempler på indikationer
A-PRF™ | Se kliniske cases med A-PRF™ her
Phlebotomy Technique
A-PRF™ | Myndighedskrav
Der er enkelte krav til autorisation, uddannelse og arbejdsgange – se mere nedenfor.
Medhjælpsregler
Journalisering
Samtykke
A-PRF™ | Krav til autorisation
A nvendelsen af A-PRF™ / I-PRF™ i en tandlægepraksis stiller en række krav til autorisation, uddannelse og arbejdsgange. I vedlagte orienteringsskrivelse finder du baggrund og henvisninger til lovgivning og bekendtgørelser, samt orientering om arbejdsgange og skabeloner udarbejdet for at lette dit arbejde!A-PRF™ teknikken involverer arbejdsopgaver indenfor et andet autorisationsområde (lægeforbeholdt virksomhed) udført under medhjælpsreglerne. I den forbindelse følger der særlige krav til journalisering og tilsyn, som du skal være opmærksom på at have afklaret med den læge, som knytter sin autorisation til klinikken.
A-PRF™ | Vi hjælper dig
Arbejdsgange, informationer til patienterne, kursus i blodudtagning osv. vi gør det enkelt at arbejde med PRF.
PRF | Orientering før opstart
Kommunikation omkring anvendelse af blod i behandlingen
PRF | Patient information
Kommunikation omkring anvendelse af blod i behandlingen
PRF | Kursus i blodudtagning til behandling
Læge superviseret kursus i blodudtagning til behandling.
PRF | Arbejdsgange
Step by Step arbejdsgangsbeskrivelse for anvendelse af A-PRF™ og i-PRF™
The A-PRF+ / I-PRF
Steak technique
A-PRF™ | Artikler
Rundt om på puredent.dk kan du finde artikler og litteraturoversigt. Nedenfor fremhævet en række artikler.
PRF | Low Speed Concept
Optimized Platelet Rich Fibrin With the Low Speed Concept: Growth Factor Release, Biocompatibility and Cellular Response
PRF | GF release
Comparative release of growth factors from PRP, PRF, and advanced-PRF
PRF | litteraturoversigt
+350 artikler om PRF
A-PRF™ | Udstyr
A-PRF™ | centrifuge
A-PRF™ | PRF boks og instrumenter
A-PRF™ | Tubes
DUO centrifuge
A-PRF™ | Videos
A-PRF™ | intro to PRF box
Short introduction creation of A-PRF™ membranes using the PRF box.
A-PRF | bone graft created from membranes and bonematerials
Bone particles mixed with A-PRF™ membrane cut into pieces formed into a graft. i-PRF™ is then injected onto the graft and it clots
A-PRF | Sandwich graft
Combination of A-PRF™ and i-PRF™ in creating bone grafts from bone substituts.
A-PRF™ | Se alle videoer her
A-PRF™ | Kliniske cases
A-PRF™ | Se kliniske cases med A-PRF™ her
A-PRF™ | literatur highlights
A-PRF™ | Advantages of PRF over PRP
- No biochemical handling of blood.
- Simplified and cost-effective process.
- Use of bovine thrombin and anticoagulants not required.
- Favorable healing due to slow polymerization.
- More efficient cell migration and proliferation.
- PRF has supportive effect on immune system.
- PRF helps in hemostasis.
- Release of growth factors for more than 10 days
- Higher overall growth factor release than PRP
A-PRF™ | Litterature
- Publication overview 2001 – 2016, (include pubmed links)
- The Low Speed Concept
- Classification of platelet concentrates..
- Comparative release of growth factors from PRP, PRF, and advanced-PRF.
- PRF a second gen – part 1.pdf
- PRF a second gen – part 2.pdf
- PRF a second gen – part 3.pdf
- PRF a second gen – part 4.pdf
- PRF a second gen – part 5.pdf
